Session 1: ENT: Laryngopharyngeal Reflux
Wednesday, April 24, 9:00 – 10:30 am
Auditorium Léon Hirsch
Chairs: Jonathan Bock (USA) – Nikki Johnston (USA)
- Is HEMII-pH the gold-standard diagnostic tool for LPR? – Jennifer Aoun (Belgium)
- Why does the clinical presentation and treatment response of patients with suspected LPR vary? – Inna Husain (USA)
- How does pepsin cause mucosal damage in the context of weakly or nonacid refluxate? – Tina Samuels (USA)
- What is the status of pepsin inhibitors for the treatment of LPR? – Nikki Johnston (USA)
- What is the evidence of surgical fundoplication and Linx system in gastro-esophago-laryngopharyngeal reflux? – Edgar J. Figueredo (USA)
- What is the role of the UES in LPR? – David M. Richards (USA)
Session 2: Barrett’s Esophagus – Current State of the Art
Wednesday, April 24, 9:00 – 10:30 am
Auditorium Kagame
Chairs: Wayne Phillips (Australia) – Dagmar Kollmann (Austria) – George Triadafilopoulos (USA) – Kenneth J. Vega (USA) – Bruno Zilberstein (Brazil)
- Introduction & case presentation – George Triadafilopoulos (USA) – Margaret Zhou (USA)
- The current landscape of epidemiology & natural history – Kenneth J. Vega (USA)
- How is Barrett’s esophagus defined by pathology around the world? – Qin Huang (USA)
- What is the cell of origin for Barrett’s esophagus? – Wayne Phillips (Australia)
- What is the current ideal screening strategy for Barrett’s esophagus? – Hiroshi Mashimo (USA)
- Which Barrett’s esophagus patients should be ablated & by what technique? – Eun Ji Shin (USA)
- What is the role for surgery in the management of Barrett’s esophagus? – Dagmar Kollmann (Austria)
Session 3: Most important esophageal issues affecting my country
Wednesday, April 24, 9:00 – 10:30 am
Auditorium Lindbergh
Chairs: Justin Y. Y. Lee (Malaysia) – Adriana Lazarescu (Canada)
Moderator: Marcelo F. Vela Aquino (USA)
What is the most important esophageal issue affecting my country now & in the next 20 years?
- Daphne Ang (Singapore)
- John O. Clarke (USA)
- Luigi Bonavina (Italy)
- Serhat Bor (Turkey)
- Yves Borbely (Switzerland)
- Italo Braghetto (Chile)
- Hon Chi Yip (Hong Kong)
- Valter N. Felix (Brazil)
- Matthew Read (Australia)
- Jose M. Remes-Troche (Mexico)
- Russell E. White (Kenya)
- Rona Marie Lawenko (Philippines)
Session 4: Pilot Centers (1)
Wednesday, April 24, 11:00 am – 12:30 pm
Auditorium Léon Hirsch
- Robert Giuli (France)
- Nikki Johnston (USA) – Jonathan Bock (USA)
- Rahul Bharadwaj (Malaysia) demo
- Justin Y. Y. Lee (Malaysia)
New Pilot Centers: (recently onboard)
- Mehnaz Shafi (Houston, MD Anderson)
- Yinglian Xiao (Guangzhou, by Zoom)
- Yutaka Tokairin (Tokyo)
- Claire Thibault – Philippe Schultz, Department of Laryngology and Head & Neck Surgery,
University Hospital Strasbourg: Management of R-CPD (Retrograde Crico-Pharyngeus Dysfunction)
- Tutorial on Robotics: Peter Grimminger (Germany)
Session 5: Barrett’s Esophagus – Controversies and Future Directions
Wednesday, April 24, 11:00 am – 12:30 pm
Auditorium Kagame
Chairs: Wayne Phillips (Australia) – Dagmar Kollmann (Austria) – George Triadafilopoulos (USA) – Kenneth J. Vega (USA) – Bruno Zilberstein (Brazil)
- Why is esophageal cancer on the rise? – David Wang (USA)
- Personal reflections on anti-reflux surgery: 250 patients & 20 years of follow-up – Bruno Zilberstein (Brazil)
- Debates: point/counterpoint
- a) Should irregular z-lines be routinely biopsied?
- Pro – William Ravich (USA)
- Con – Nielsen Fernandez-Becker (USA)
- b) Should non-dysplastic Barrett’s esophagus patients be offered ablation?
- Pro – John O. Clarke (USA)
- Con – Allon Kahn (USA)
- c) Should all patients with Barrett’s esophagus be treated with high-dose PPI therapy and/or aspirin?
- Pro – Mark R. Fox (Switzerland)
- Con – Margaret Zhou (USA)
- d) Should all patients with nodular Barrett’s esophagus be treated with ESD or is EMR OK?
- Pro – Shai Friedland (USA)
- Con – Bryan Sauer (USA)
- e) Should all patients with Barrett’s esophagus be offered an anti-reflux operation & if so, which one?
- Pro – Valter Felix (Brazil)
- Con – Salih Samo (USA)
4. How will we approach Barrett’s esophagus in 20 years?
Wayne Phillips (Australia) – Dagmar Kollmann (Austria)
Session 6: Distinguished Abstracts Plenary
Wednesday, April 24, 11:00 am – 12:30 pm
Auditorium Lindbergh
Chairs: Suzanne S. Gisbertz (Netherlands) – Afrin N. Kamal (USA)
- Mechanisms by which topical alginates preserve esophageal epithelial barrier function during pepsin-weak acid insult – Pelin Ergun (USA)
- A novel antireflux procedure for management of gastroesophageal reflux disease: Clinical outcomes of 28 patients treated in Germany – Moustafa Elshafei (Germany)
- Diagnostic Yield for Clinically Relevant Abnormal Esophagogastric Junction Opening on Functional Lumen Imaging Probe (FLIP) at 60 mL and 70 mL Distention of 16-cm Balloon: A Case for Routine Measurement to 70 mL – Ryan Flanagan (USA)
- Impact of endoscopic pyloric dilatation on symptom relief in delayed gastric emptying after esophageal resection – use of a novel symptom response questionnaire – Mickael Chevallay (Switzerland)
- The tumor microenvironment of esophageal cancer is influenced by clinical parameters and neoadjuvant treatment – Styliani Mantziari (Switzerland)
- Unveiling the Link Between Balanced and Plant-Based Diets and Esophageal Cancer: Insights from a Chinese Population-Based Cohort Study – Shanrui Ma (China)
- Fibrin sealant for prophylaxis of cervical anastomotic leakage after McKeown esophagectomy for esophageal or esophagogastric junction cancer(PLACE030): A Phase III, Multicenter, Randomized Clinical Trial – Zhichao Li (China)
- In silico validation and algorithm development of a novel tool for clinical outcome improvement of Barrett’s Esophagus malignant progression – Joana Cardoso (Portugal)
Session 7: Oncology: Perioperative strategies in esophageal cancer
Wednesday, April 24, 2:00 – 3:30 pm
Auditorium Léon Hirsch
Chairs: Markus H. Moehler (Germany) – Bruno Zilberstein (Brazil)
Moderators: Suzanne S. Gisbertz (Netherlands) – Franco Roviello (Italy) – Thibaud Koessler (Switzerland)
- New insights in esophageal cancer biology – Stacey M. Stein (USA)
- Neoadjuvant or perioperative therapy? FLOT vs. CROSS – Sara De Dosso (Switzerland)
- Immunotherapy strategies – Markus H. Moehler (Germany)
- Targeted therapy: with or without chemotherapy – Thibaud Koessler (Switzerland)
Sessions 8 and 11: Functional Disorders
Wednesday, April 24, 2:00 – 5:30 pm
Auditorium Kagame
Hour 1
Chairs: C. Prakash Gyawali (USA) – Roberto Penagini (Italy)
Moderators: Edoardo V. Savarino (Italy) – Mark R. Fox (Switzerland) – Walter W. Chan (USA) – Ellen M. Stein (USA)
Potential important topics to discuss:
- Physiology, mucosal nerve, and innervation
- Mechanisms of esophageal hypersensitivity
- Achalasia/EGJOO evaluation vs normal transit dysphagia
- Overlap between GERD and DGBI of esophagus
- Perceptive vs transit symptoms
- Globus sensation
- Invasive intervention in functional disorders
Hour 2 (6 Questions)
Chairs: Walter W. Chan (USA) – C. Prakash Gyawali (USA)
Moderators: Marcelo F. Vela Aquino (USA) – Justin C. Y. Wu (Hong Kong)
- How do you clinically address belching or lack thereof? – Dan Sadowski (Canada)
- When to suspect and confirm the diagnosis of rumination? – Joan W. Chen (USA)
- Esophageal chest pain or heartburn: is it reflux or not? – Albis C. Hani de Ardila (Colombia)
- When nothing is “wrong” – how to approach normal transit dysphagia? – Daphne Ang (Singapore)
- Not all cough is reflux - what to do when reflux is ruled out? – Walter W. Chan (USA)
- What to do when achalasia is adequately treated but symptoms persist? – Ellen M. Stein (USA)
Hour 3 (6 Questions)
Chairs: Roberto Penagini (Italy) – Ellen M. Stein (USA)
Moderators: Justin Y. Y. Lee (Malaysia) – Braden Kuo (USA)
- Is acid suppression appropriate for treatment of disorders of gut-brain interaction? – Justin Y. Y. Lee (Malaysia)
- How to choose the right neuromodulator for esophageal DGBI? – Braden Kuo (USA)
- When talking is better than drugs: what are the roles of cognitive behavioral therapy and hypnosis? – Livia Guadagnoli (Belgium)
- Is there a role for cannabinoids in esophageal disorders? – Marcelo F. Vela Aquino (USA)
- Pins, needles and clips – when to use acupuncture and vagal nerve stimulation? – Justin C. Y. Wu (Hong Kong)
- Can digital apps and virtual reality be leveraged for esophageal disorders, or is it too soon? – Eric D. Shah (USA)
Session 9: Interventional Endoscopy (1)
Wednesday, April 24, 2:00 – 3:30 pm
Auditorium Lindbergh
Chair: Hiroshi Mashimo (USA)
1) Endoscopic hemostasis
- What are the comparative features of topical glues/sprays/gels and considerations for choosing one over the other? Mihir S. Wagh (USA)
- What are the comparative features of clips and stitching devices, and what are the considerations for choosing one over the other? – Roberto Trasolini (Canada)
- What are recent advances in management of bleeding varices? Stuart R. Gordon (USA)
- Topical versus physical closures – how do they compare? – Eun Ji Shin (USA)
2) Leaks, fistulas and perforations
- What are comparative features of various clips and stitching devices? – Ashish A. Sharma (USA)
- How are various stents used for optimal management? – Jon O. Wee (USA)
- What are main considerations for Endovacc procedure? – Russel E. White (Kenya)
- Considering all maneuvers, what optimal decision path (evidence-based) should be taken in managing perforations, leaks, and fistulas? – Matthew Read (Australia)
3) Esophageal Zenker’s diverticulum
- What are optimal studies in diagnosis of Zenker’s diverticulum and guiding therapy? Francis J. Scholz (USA)
- What are Z-POEM particular indications, comparative data to surgery – Stuart R. Gordon (USA)
- What are known complications of Z-POEM and special considerations – Mihir S. Wagh (USA)
- Surgical options and when NOT to perform Z-POEMS – Derrick R. Randall (USA)
4) Ablative therapies for esophageal neoplasms: burn, freeze, resect
- What are considerations of pathogenesis relevant to ablation of neoplasm in esophageal adenocarcinoma versus squamous cell cancer that influence screening, surveillance and therapy? – Qin Huang (USA)
- What are the various thermoablative methods and cryoablative methods for neoplastic tissues and special considerations for choosing one over the other? – Roberto Trasolini (Canada)
- Resections: EAC and SCC what special considerations for choosing one over the other? – Hon-Chi Yip (Hong Kong)
- What are promising advanced endoscopic imaging tools in evaluation of neoplasm? – Hiroshi Mashimo (USA)
- What are considerations of ablative techniques in reducing recurrence? – Eun Ji Shin (USA)
- When to burn, freeze, or resect? – Shai Friedland (USA)
Session 10: Oncology: Oncologic strategies in exceptional cases
Wednesday, April 24, 4:00 – 5:30 pm
Auditorium Léon Hirsch
Chairs: Markus H. Moehler (Germany) – Matthew Read (Australia) – Thibaud Koessler (Switzerland)
Moderators: Suzanne S. Gisbertz (Netherlands) – Franco Roviello (Italy) – Thibaud Koessler (Switzerland)
- Optimal protocol for clinical complete responders – Sara De Dosso (Switzerland)
- Immunotherapy or targeted therapy for resectable esopahageal cancer – Markus H. Moehler (Germany)
- The role of immune therapy in palliative esophageal cancer treatment – Jonas Feilchenfeld (Switzerland)
- Optimal protocol for locoregional recurrence – David Wang (USA)
- New biomarkers: from bench to bedside – Rupert Langer (Austria)
- Wait and see strategy after radiochemotherapy – Suzanne S. Gisbertz (Netherlands)
- Optimal surveillance of esopohageal cancer patients – Mickael Chevallay (Switzerland)
Session 12: Interventional Endoscopy
Wednesday, April 24, 4:00 – 5:30 pm
Auditorium Lindbergh
Chair: Hiroshi Mashimo (USA)
1) Endoscopic management of benign strictures
- What are various methods of dilations and considerations for optimized use? – Eric G. Sheu (USA)
- What are the optimal endoscopic management of refractory/recurrent stricture – Andrew Chang (USA)
- What radiological studies show to help guide management – Peter Pokieser (Austria)
- What ablation tool to chose: when and why – Roberto Trasolini (Canada)
2) Endoscopic management of malignant obstruction
- What imaging evaluations are most helpful prior to endoscopy? – Francis J. Scholz (USA)
- Stents, Dilations, and Ablations: which to choose for optimal management?
- Are there differences in durability of endoscopic ablations comparing SCC to EAC? – Hon-Chi Yip (Hong Kong)
- Complications of endoscopic therapies and how to manage in setting of esophageal cancer – Michael Mwachiro (Kenya)
3) Endoscopic treatments of GERD
- What endoscopic treatments are available and how do they compare? – Wai-Kit Lo (USA)
- What are the roles of motility studies in optimized choice of endoscopic treatment? – Yan Jiang (USA)
- What is the role of endoscopic evaluation in choice of treatment? – Nicole Cherng (USA)
- Considerations to opt surgery over endoscopic treatments – Ann DeBord-Smith (USA)
4) Endoscopic treatments of achalasia
- What radiological studies and findings are helpful in guiding mode of treatment? – Francis J. Scholz (USA)
- What endoscopic options do we have and critical review of manometry and anatomy in choice of therapy? – Georgios Mavrogenis (Greece)
- What is the evidence for and against Botox treatments? – John O. Clarke (USA)
- What endoscopic assessments (careful retroflexion? FLIP?) can better guide therapy? – Salih Samo (USA)
- What are considerations in dealing with return of dysphagia after therapy? – Jon O. Wee (USA)
- What is a rational approach to selection of achalasia management – Hiroshi Mashimo (USA)
Session 13: Young Investigators Research
Thursday, April 25, 9:00 – 10:30 am
Auditorium Léon Hirsch
Chair: Sheraz Markar (UK)
- Surgical quality assurance: moving from clinical trial to real world – Sheraz Markar (UK)
- The future of robotic surgery – Maria Bencivenga (Italy)
- Role of AI in benign esophageal diseases – Pierfrancesco Visaggi (Italy)
Session 14: Stenosis Medico-Surgical dilemmas
Thursday, April 25, 09:00 – 10:30 am
Auditorium Kagame
Part I:
Chair: Justin Y. Y. Lee (Malaysia)
Moderators: Rona Marie Lawenko (Philippines) – Peter Pokieser (Austria)
- Characterisation of benign stenoses at all levels from the UES to the LES – Peter Pokieser (Austria)
- What is the role of surgery in benign stenosis? – Junaidi Hamidi (Malaysia)
- Roles of endoscopy and motility in caustic esophageal stenosis – Justin Y. Y. Lee (Malaysia)
- Radiology role in the complications of bariatric surgery including sleeve stenosis and gastric bypass herniations of the gastric pouch – Peter Pokieser (Austria)
- What is the preoperative role of motility testing? – Rona Marie Lawenko (Philippines)
- What is my approach for Zenker Diverticulum? – Stefano Siboni (Italy)
Discussion
Session 15: Techniques and Tips in Esophageal Practice (1)
Thursday, April 25, 9:00 am – 12:30 pm
Auditorium Lindbergh
I: GERD, Antireflux Surgery, and Esophageal Cancer
Chairs: Roger P. Tatum (USA) – Afrin N. Kamal (USA)
- The retroflexed endoscope: the Hill flap, cardia, and subtle strictures – Hiroshi Mashimo (USA)
- PPIs are no longer working – no problem! Tips on when to use PCABs in medical practice – Adriana Lazarescu (Canada)
- Optimal technique for cTIF – Reginald C. W. Bell (USA)
- Robotic repair in reoperative antireflux surgery—leveraging the advantages of robotic technique over standard laparoscopy – Mickael Chevallay (Switzerland)
- When reflux progresses – how to approach Barrett’s esophagus: Screening and Surveillance – Allon Kahn (USA)
- Are you sure it’s reflux? How to approach management of laryngopharyngeal reflux – Walter W. Chan (USA)
- Management of cervical anastomotic leak after transhiatal esopahgectomy – Lorrie A. Langdale (USA)
Session 16: Young Investigators Research
Thursday, April 25, 11:00 am – 12:30 pm
Auditorium Léon Hirsch
Chair: Sheraz Markar (UK)
- Liquid biopsy in oesophageal cancer pathway – Mickael Chevallay (UK)
- Cancer survivorship – Jessie A. Elliott (Ireland)
- Inhaled fosamprenavir for the treatment of airway reflux – Alexandra Lesnick (USA)
- What trials do we look out for in 2024/2025 – Lana Fourie (Switzerland)
Session 17: Stenosis Medico-Surgical dilemmas
Thursday, April 25, 11:00 am – 12:30 pm
Auditorium Kagame
Part II:
Chair: Justin Y. Y. Lee (Malaysia)
Moderators: Hon-Chi Yip (Hong Kong) – Junaidi Hamidi (Malaysia)
- Evolution in esophagectomy: How to achieve better outcome via minimally invasive approach? – Edward Cheong Chee Keong (Singapore)
- Minimally invasive surgery in the era of multimodality treatment of esophageal cancers – Peter Grimminger (Germany)
- Clinical Practice Guidelines for EGJ cancer (Upper GI Oncology Summit 2023): What is the role of endoscopy? Justin Y. Y. Lee (Malaysia)
- How do I perform ESD in pre-malignant stenotic conditions? Tips and Tricks – Hon-Chi Yip (Hong Kong)
- How do I manage leakage after esophagectomy? – Christian A. Gutschow (Switzerland)
- Optimising nutrition in malignant esophageal stenosis – Junaidi Hamidi (Malaysia)
Discussion
Session 18: Techniques and Tips in Esophageal Practice (2)
Thursday, April 25, 11:00 am – 12:30 pm
Auditorium Lindbergh
II: Motility and Other Esophageal Problems
Chairs: Roger P. Tatum (USA), Afrin N. Kamal (USA)
- Eosinophilic esophagitis in 2024 – how I approach management in complex disease – Jennifer Horsley Silva (USA)
- How to best use intraoperative EndoFLIP in Heller myotomy and POEM – Jacob R. Moremen (USA)
- Transhiatal approach to epiphrenic diverticulum – Renato V. Soares (Brazil)
- This twitches too much. Management approach to esophageal spasm and Jackhammer esophagus – Anh D. Nguyen (USA)
- Techniques for challenging hiatal repair in paraesophageal hernia – Medhat Y. Fanous (USA)
- Use of motility and pH testing for procedure selection before bariatric surgery – Judy Y. Chen-Meekin (USA)
- Vomiting or Regurgitation? Use of motility testing to identify rumination syndrome – Daniel Sifrim (UK)
Session 19: Eosinophilic esophagitis – current understanding
Thursday, April 25, 2:00 – 3:30 pm
Auditorium Léon Hirsch
Chairs: Emily McGowan (USA) – Bryan Sauer (USA) – Jennifer L. Horsley-Silva (USA) – Neilsen Fernandez-Becker (USA)
- The EoE epidemic: history & epidemiology – Kristle Lynch (USA)
- Pathology of EoE: definitions & findings beyond eosinophilia – Paul Swanson (USA
- EoE & the allergy diathesis: proposed mechanisms & allergy testing – Emily McGowan (USA)
- Approaches to dietary elimination for treatment of EoE – Nielsen Fernandez-Becker (USA)
- Understanding the EoE medical treatment arsenal: topical steroids, dupilumab & novel agents – Jennifer L. Horsley-Silva (USA)
- The role of the endoscopist in the management of the EoE patient – Bryan Sauer (USA)
Session 20: Esophageal Cancer: Squamous Cell Carcinoma
Thursday, April 25, 2:00 – 3:30 pm
Auditorium Kagame
Introduction: Andrew Chang (USA) – Giovanni de Manzoni (Italy)
Chairs: Kiran H. Lagisetty (USA) – You-Sheng Mao (China) – Philippe Morel (Switzerland)
Moderators: Russel E. White (Kenya) – Rubens A. A. Sallum (Brazil)
- Active surveillance rather than resection is appropriate for patients with esophageal SCC who demonstrate complete clinical response after completing neoadjuvant therapy? – Kiran H. Lagisetty (USA)
- Indications for open esophagectomy? – Arnulf Hölscher (Germany)
- Are there still surgical indications for proximal esophageal cancer? – Rishindra M. Reddy (USA)
- Technique, indications and results for transcervical esophagectomy – Bastiaan Klarenbeek (Netherlands)
- The usefulness of a bilateral trans-cervical pneumomediastinal approach for mediastinoscopic radical esophagectomy – Yutaka Tokairin (Japan)
- What is the best way to treat anastomotic leakage: cervical anastomosis? – Jon O. Wee (USA)
Session 21: Update in GI Clinical Pharmacology
Thursday, April 25 – 2:00 – 3:30 pm
Auditorium Lindbergh
Chairs: Carmelo Scarpignato (Malta) – C. Prakash Gyawali (USA)
- Advances in acid suppression: are P-CABs the new frontier? – Carmelo Scarpignato (Malta)
- Prokinetics for upper GI tract: where are we and where are we going? – Braden Kuo (USA)
- Esophageal mucosal protection: a new avenue for treatment and prevention of mucosal lesions – Daniel Sifrim (UK)
- Visceral analgesics: ho do they work and when should be employed – C. Prakash Gyawali (USA)
- Nutraceuticals: do they have a role in esophageal diseases? – David Wang (USA)
Session 22: Eosinophilic esophagitis – debates & discussions
Thursday, April 25, 4:00 – 5:30 pm
Auditorium Léon Hirsch
Chairs: Emily McGowan (USA) – Bryan Sauer (USA) – Jennifer L. Horsley-Silva (USA) – Neilsen Fernandez-Becker (USA)
- Do we know the natural history of EoE? – Adriana Lazarescu (Canada)
- What is the best initial therapy for the symptomatic EoE patient?
I. Proton pump inhibitors – Walter W. Chan (USA)
II. Dietary elimination – Mark R. Fox (Switzerland)
III. Swallowed topical steroids – Brent Hiramoto (USA)
IV. Dupilumab – John O. Clarke (USA)
- Are there any non-invasive means to assess inflammation? – Edoardo V. Savarino (Italy)
- Should all EoE providers be performing FLIP for EoE endoscopies? – Abraham Khan (USA)
- Does chronic EoE-related esophageal inflammation increase the risk of cancer? – David Wang (USA)
- How will we treat EoE in 10 years? – Emily McGowan (USA)
Session 23: Esophageal Cancer: Adenocarcinoma
Thursday, April 25, 4:00 – 5:30 pm
Auditorium Kagame
Introduction: Arnulf Hölscher (Germany)
«In memoriam Professor Dr. Jörg Rüdiger Siewert – Vita and SIEWERT classification»
Chairs: Stefan P. Mönig (Switzerland) – Giovanni de Manzoni (Italy)
Moderators: Arnulf Hölscher (Germany) – Bruno Zilberstein (Brazil) – Edward Cheong Chee Keong (Singapore) – Marc van Berge Hennegouwen (Netherlands)
- Decision making in Siewert II Adenocarcinoma: gastrectomy versus esophagectomy? – Stefan P. Mönig (Switzerland)
- Is thoracic duct resection indicated in adenocarcinoma of the esophagus? – Paolo Morgagni (Italy)
- Lymph node dissection of the upper mediastinum – indicated in all patients? – Paul M. Schneider (Switzerland)
- Which is the evidence-based surgical approach: transhiatal, left thoracoabdominal, two-stage transthoracic or three-stage transthoracic for distal esophageal adenocarcinoma? – Andrew Davis (UK)
- F Is cT1 still a surgical disease, and in which cases? – Maria Bencivenga (Italy)
- What is the best way to treat anastomotic leakage: intrathoracic anastomosis? – Marc van Berge Hennegouwen (Netherlands)
Session 24: Emerging Innovation, AI, and Digital Technology in Esophagology
Thursday, April 25, 4:00 – 5:30 pm
Auditorium Lindbergh
Chairs: Eric D. Shah (USA) – Austin L. Chiang (USA)
- How do you cross the chasm to adopting new esophageal technologies? – Eric D. Shah (USA)
- How do you commercialize your idea into a new technology? – Austin L. Chiang (USA)
- Multi-Scale Medical Robotics Center: How can you simulate new surgical esophageal innovations? – Hon Chi Yip (Hong Kong)
- How artificial intelligence will revolutionize minimally invasive surgery? – Jacques Marescaux (France)
- How do you translate open surgery to new minimally invasive foregut surgery techniques? – Rishindra M. Reddy (USA)
- What is the next big medical device in esophagus care? – Lee L. Swanström (France)
- Is artificial intelligence useful to identify Barrett’s esophagus?
- Can artificial intelligence be leveraged to identify esophageal motility disorders? – Pierfrancesco Visaggi (Italy)
- How can digital apps augment esophageal care delivery? – Kristle L. Lynch (USA)
Session 25: Guest Society – American Foregut Society
Friday, April 26, 9:00 – 10:30 am
Auditorium Léon Hirsch
Chairs: Jacob R. Moremen (USA) – Abraham Khan (USA)
- History of American Foregut Society (AFS) – John C. Lipham (USA)
- Role of Esophageal Function Testing Post-fundoplication – Reena Chokshi (USA)
- Post-Fundoplication Syndromes: Surgical Management – John C. Lipham (USA)
- Post-Myotomy Achalasia: Surveillance and Approach to Persistent Symptoms – Joshua Sloan (USA)
- Post-Myotomy Failure: Surgical Management – Jacob R. Moremen (USA)
- Discussion
Session 26: Obesity and the Esophagus (1)
Friday, April 26, 9:00 – 10:30 am
Auditorium Kagame
Chairs: Ralph Peterli (Switzerland) – Minoa K. Jung (Switzerland)
- Metabolic bariatric Surgery: State of the art- choice of procedures and outcomes – Ralph Peterli (Switzerland)
- Roux-en-Y gastric bypass in superobese patients: what are the results and are there alternatives? – Styliani Mantziari (Switzerland)
- Global Benchmarks in robotic bariatric surgery: what are the quality standards? – Minoa K. Jung (Switzerland)
- Metabolic bariatric endoscopy: Current procedures and long-term results? – Silvana Perretta (France)
- Early complications after primary bariatric surgery and how to manage them? – Pouya Iranmanesh (Switzerland)
Session 27: ENT: Airway Reflux
Friday, April 26, 9:00 – 10:30 am
Rooms C.L.E.M.
Chairs: Thomas L. Carroll (USA) – Nikki Johnston (USA)
- When should you use PPIs for LPR and when should you not? – Serhat Bor (Turkey)
- What is the rate of pepsin saliva positivity in asymptomatic individuals and does multi-sampling help us choose treatment? – Jacqueline Allen (New Zealand)
- How do anti-pepsin therapies protect against reflux-mediated damage? – Simon Blaine-Sauer (USA)
- What is the aetiologic evidence for reflux in adult and pediatric subglottic stenosis? – Derrick R. Randall (Canada)
- What are the interactions between laryngopharyngeal reflux and chronic cough? – Jonathan Bock (USA)
- How do we determine when the cause of an LPR symptom is due to other laryngeal pathology? – Thomas L. Carroll (USA)
- What has been learned about GERD from the lung transplant world? – Sumeet Mittal (USA)
Session 28: Pilot Centers (2)
Friday, April 26, 11:00 am – 12:30 pm
Auditorium Léon Hirsch
- Robert Giuli (France)
- Rahul Bharadwaj (Malaysia) with demo
Candidates:
- Silvana Perretta (France) – Strasbourg, IHU
- Dirk Domagk – Ingo Herrmann (Germany) – Muenster/Dusseldorf
- Richard Gurski (Brazil) Rio Grande do Sul – (Presentation by Bruno Zilberstein (Brazil))
Debate: Perspectives for the future – Expansion of the Platform
- Russell E. White (Kenya)
- Rahul Bharadwaj (Malaysia)
- George Triadafilopoulos (USA)
Session 29: Obesity and the Esophagus (2)
Friday, April 26, 11:00 am – 12:30 pm
Auditorium Kagame
Chairs: Ralph Peterli (Switzerland) – Minoa K. Jung (Switzerland)
- Barrett’s esophagus after bariatric surgery: de novo, worsening or resolution? – Judy Y. Chen-Meekin (USA)
- What are the benefits and complications of medical treatment of obesity? – Nayna Lodhia (USA)
- Association of Achalasia with Morbid Obesity: what is the best treatment? – Ann DeBord-Smith (USA)
- What is the impact of bariatric surgery and weight loss on occurence of esophageal cancer? – Eun Ji Shin (USA)
- Morbid obesity and reflux burden: what is the effect of bariatric surgery on GERD and esophageal motility? – Brent Hiramoto (USA)
- What investigations after bariatric surgery for upper abdominal pain? – Mark R. Fox (Switzerland)
Session 30: EGJOO (Esophago-Gastric Junction Outflow Obstruction) in 2024
Friday, April 26, 11:00 am – 12:30 pm
Rooms C.L.E.M.
Chairs: Justin C. Y. Wu (Hong Kong) – Kristle L. Lynch (USA)
- Is EGJOO an achalasia spectrum disorder? – Enrique Coss-Adame (Mexico)
- How do you identify anatomical EGJOO? – Stefano Siboni (Italy)
- What is the role of opioids in EGJOO? – Christopher D. Velez (USA)
- How should FLIP be used in suspected EGJOO? – Abraham Khan (USA)
- How can HRM provocative maneuvers be leveraged to diagnose EGJOO? – Pierfrancesco Visaggi (Italy)
- Is medical management feasible in motor EGJOO? – Kristle L. Lynch (USA)
- Is pneumatic dilation useful in EGJOO? – Joshua Sloan (USA)
- Which EGJOO patients need a myotomy? – Stefano Siboni (Italy)
- What is the prognosis of EGJOO? – Sravanya Gavini (USA)
- EGJOO in 2024: where do we go from here? – C. Prakash Gyawali (USA)
Session 31: Updates in GERD
Friday, April 26, 2:00 – 3:30 pm
Auditorium Léon Hirsch
Session I:
Chairs: C. Prakash Gyawali (USA), Adriana Lazarescu (Canada)
- Wireless pH monitoring vs catheter-based pH-impedance – which is optimal to evaluate each reflux symptoms? – Daniel Sifrim (UK)
- Is ambulatory reflux monitoring needed before anti-reflux surgery if LA grade B esophagitis is found on endoscopy? – Robert B. Yates (USA)
- Is non-acid reflux clinically relevant and when should we look for it? – Daniela Jodorkovsy (USA)
- SAP and SI – which symptom-reflux association metric(s) on ambulatory reflux monitoring should be used and how? – Kenneth J. Vega (USA)
- How reliable and clinically relevant are upright vs supine and proximal reflux metrics on ambulatory reflux monitoring? – Adriana Lazarescu (Canada)
- Does endoscopic mucosal impedance have a role in the clinical evaluation of reflux? – Marcelo F. Vela Aquino (USA)
- When should MNBI and PSPW be routinely incorporated into reflux testing? – Edoardo V. Savarino (Italy)
- Can pepsin be used as a reliable clinical marker for reflux? – Wai-Kit Lo (USA)
- How should esophageal motility assessment be used in the evaluation of reflux symptoms? – Amit Patel (USA)
- How should reflux be diagnosed in 2024? – C. Prakash Gyawali (USA)
Session 32: State of the Art: Surgery
Friday, April 26, 2:00 – 3:30 pm
Auditorium Kagame
Chairs: Arnulf Hölscher (Germany) – Giovanni de Manzoni (Italy)
Moderators: Luigi Bonavina (Italy) – Yves Borbely (Switzerland) – Stefan P. Mönig (Switzerland) – Suzanne S. Gisbertz (Netherlands)
- Surgery for Achalasia – Ines Gockel (Germany)
- Surgery for Reflux and Hiatal hernia – Christian A. Gutschow (Switzerland)
- Discussion: Luigi Bonavina (Italy) – Yves Borbely (Switzerland)
- Surgery for Adenocarcinoma of the esophagus – Sallum Rubens (Brazil)
- Surgery for squamous cell carcinoma of the esophagus – Simon Y. K. Law (Hong Kong)
- Discussion: Stefan P. Mönig (Switzerland) – Suzanne S. Gisbertz (Netherlands)
Session 33: Pathology 1
Friday, April 26, 2:00 – 3:30 pm
Auditorium Lindbergh
Esophagitis and Barrett's esophagus
Chairs: Dhanpat Jain (USA) – Rupert Langer (France)
- What is the clinical significance of making a diagnosis of sloughing esophagitis? – Dhanpat Jain (USA)
- What is the clinical significance of making a diagnosis of lymphocytic esophagitis? – Monika Tripathi (Canada)
- What is the clinical significance of making a diagnosis of lichenoid esophagitis? – Maryam K. Pezhouh (Canada)
- What are the similarities and differences between lymphocytic and eosinophilic esophagitis? – Sara Hafezi Bakhtiari (Canada)
- Is there any role of counting eosinophils in EOE patients? – Maryam Pezhouh (USA)
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Is there any significance in reporting sub-epithelial fibrosis on biopsies in EOE patients? – Kevin M. Waters (USA)
Q&A
- Should goblet cells be required for the diagnosis of Barrett's esophagus? – Maha Guindi (USA)
- What is diagnostic and prognostic role of p53 IHC in BE and dysplasia? – Huang Qin (USA)
- What are the common challenges in evaluating margins for dysplasia and cancer in esophageal EMR/ESD? – Deyali Chatterjee (USA)
- What is the current status of AI and ML application in Barrett's esophagus? – Sara Hafezi Bakhtiari (Canada)
Q&A
Session 34: Updates in GERD
Friday, April 26, 4:00 – 5:30 pm
Auditorium Léon Hirsch
Session II:
Chairs: Walter W. Chan (USA) – Kerry B. Dunbar (USA)
- Chronic proton pump inhibitor use is bad for my health – myth or fact? – Lawrence F. Borges (USA)
- What is the efficacy of PPI for different typical reflux symptoms? – John O. Clarke (USA)
- How effective is acid suppression therapy for cough and pulmonary symptoms? – Walter W. Chan (USA)
- Does acid suppression therapy have a role in management of reflux hypersensitivity and functional heartburn? C. Prakash Gyawali (USA)
- Should on-demand acid suppression be used in treatment of reflux symptoms? – Kerry B. Dunbar (USA)
- What is the role of GABA agonists in the management of reflux symptoms? – Reena Chokshi (USA)
- When should mucosal coating agents be used in reflux management? – Rona Marie Lawenko (Philippines)
- How does PCAB compare to PPI in endoscopic reflux healing? – Sravanya Gavini (USA)
- Are PCAB better than PPI in reflux symptoms control? – Ellen M. Stein (USA)
- What are effective therapies for nocturnal acid breakthrough for patients on twice daily PPI? – Irene Sonu (USA)
- When should PCAB be considered? – Jose M. Remes-Troche (Mexico)
Session 35: Minimally Invasive and Robotic Esophageal Surgery
Friday, April 26, 4:00 – 5:30 pm
Auditorium Kagame
Chairs: Peter Grimminger (Germany) – Suzanne S. Gisbertz (Netherlands)
Moderators: Simone Giacopuzzi (Italy) – Rubens A. A. Sallum (Brazil) – Sheraz Markar (UK) – Yutaka Tokairin (Japan)
- How to define and assess the quality of minimally invasive esophagectomy? – Sheraz Markar (UK)
- Minimally invasive approach to Siewert III – Franco Roviello (Italy)
- Does adopting a minimally invasive approach to esophageal cancer require the use of robotic surgery? – Simone Giacopuzzi (Italy)
- Is there a direct and inseparable link between ERAS and minimally invasive approach in esophageal surgery? – Shaun Preston (UK)
- RACE procedure: an option to learn? – Rubens A. A. Sallum (Brazil)
- Is there a place for minimal invasive limited resection in esophagogastric junction cancer? – Felix Berlth (Germany)
Session 36: Pathology 2
Friday, April 26, 4:00 – 5:30 pm
Auditorium Lindbergh
Esophageal carcinoma
Chairs: Dhanpat Jain (USA) – Rupert Langer (France)
- Should we routinely test for DNA-MMR/MSI esophageal carcinoma (SCC/Adenocarcinoma) – Florence Renaud (France)
- Should we routinely test for SMARC4/INI in esophageal carcinomas – Monika Tripathi (Canada)
- Should we test for PDL-1 in esopageal carcinoma (SCC/Adenoca) and how to report PDL-1 – Paul E. Swanson (USA)
- What is the status of claudin 18.2 testing in esophageal carcinoma – Dhanpat Jain (USA)
- What are the next diagnostic/prognostic and therapeutic biomarkers for esophageal carcinoma after claudin 18.2 and PD-L1? – Florence Renaud (France)
- Any role of reporting "Her2 low" in GEJ adenocarcinoma – Maha Guindi (USA)
- What is the role of NGS in esophageal carcinoma? – Rupert Langer (Austria)
- What is upcoming and novel biomarkers for progression in BE and dysplasia? – Catherine J. Streutker (Canada)
- What is the current status of AI and ML application in the pathologic diagnosis of esophageal carcinoma – Bastian Dislich (Switzerland)
- What is the current status of AI and ML application in assesment of tumor regression post neo-adjuvant treated esophageal carcinoma – Deyali Chatterjee (USA)
- What is the role of liquid biopsy in esophageal carcinoma? – Bastian Dislich (Switzerland)
Q&A